Oleuropein Benefits
Oleuropein is a chemical found in olive leaves. Many studies have been done on this compound and it has shown that it has strong medicinal properties.
The benefits of oleuropein are amazing ! This substance is antibiotic, antibacterial, antifungal, and antiviral, and it also increases the body’s immune response. In the continuation of this article, we will discuss the full benefits of oleuropein, this amazing substance !
What is Oleuropein and what Are its Properties?
Oleuropein is a natural compound and is abundant in olive leaves and oil.
Olive is known for its antioxidant and anti-inflammatory properties. Oleuropein powder is the concentrated form of this useful substance and is extracted from olive leaves. Its powder form is used for easy consumption and the ability to add to various products.
Some people use this substance for medicinal purposes because it has been shown in many studies to kill bad bacteria; Unlike synthetic antibiotics that kill both bad and good bacteria. Another benefit of oleuropein is its strong antioxidant properties, thus reducing cell damage by preventing the creation of free radicals in the body.
Oleuropein Profile
name | oleuropein |
CAS NO | 32619-42-4 |
Chemical formula | C25H32O13 |
material grade | >98% |
Molecular weight | 540.51 |
Maintenance | room temperature |
How to make Oleuropein
There are three stages in the olive fruit growth process:
- Growth stage: oleuropein accumulation occurs in this stage.
- Green maturity stage: reduction of chlorophyll and oleuropein levels occurs.
- Black maturity stage: the appearance of anthocyanins and the decrease of oleuropein levels occur.
Therefore, oleuropein is abundant in stages 1 and 2; To the extent that it reaches 14% of dry matter in these stages.
Oleuropein Benefits
The properties and effects of this chemical compound are many. As mentioned, many antioxidant, anti-inflammatory, anti-cancer, anti-atherogenic, anti-microbial and anti-viral properties have been considered for oleuropein, which will be fully described below.
These properties have made oleuropein a suitable food supplement in many countries commercially.
1.Unique Antioxidant Property
Oleuropein strongly inhibits the oxidation of copper sulfate in LDL lipoproteins. Also, this substance has the ability to remove nitric oxide and increase nitric oxide synthase in the cell.
Hypochlorous acid is an oxidative substance inside the body that is created by neutrophil myeloperoxidase at the site of inflammation and damages proteins such as enzymes. Oleuropein has the ability to inhibit this substance.
2.Oleuropein is a strong Anti-inflammatory
Other benefits of oleuropein include its anti-inflammatory properties. Chronic inflammation is a contributing factor to many diseases, including arthritis, autoimmunity, inflammatory bowel diseases, and certain types of cancer. Research has shown that oleuropein modulates inflammatory pathways.
It also reduces pro-inflammatory molecules such as cytokines and enzymes such as cyclooxygenase and lipoxygenase. By controlling these inflammatory processes, inflammation is reduced throughout the body.
3.Skin Protection
During the research conducted on the effect of olive oil on the skin, it has been determined that the phenolic compounds of olive oil have an antioxidant and direct effect on the skin tissue. Especially oleuropein, which is also a free radical scavenger of the skin surface.
The researchers stated that the preventive effects of oleuropein on chronic skin damage and UVB-induced tumor growth may occur due to the inhibition of VEGF, MMP-2, MMP-9 and MMP-13 through the reduction of COX-2 levels.
4.Anticancer properties of Oleuropein
One of the benefits of oleuropein is that, according to many studies, the constituents of olive oil are known to be effective factors in preventing the occurrence and development of cancer.
Research has shown that oleuropein can inhibit the growth of LN-18 cells. It has been proven in many studies that oleuropein aglycone is a very strong phenolic compound in reducing the viability of growing breast cancer cells.
5.Oleuropein and Cardiovascular Health
Today, one of the main causes of death in the world is cardiovascular diseases, and oleuropein has shown to be effective in protecting heart health.
Research results state that oleuropein may lead to a decrease in blood pressure, which is one of the risk factors for heart disease. By relaxing the blood vessels and improving the endothelial process, the inner lining for the blood vessels responsible for controlling blood flow is achieved.
Anti-inflammatory and antioxidant properties are among the benefits of oleuropein in maintaining cardiovascular health. Oxidative stress and inflammation are important factors in plaque formation in arteries, which may lead to heart attacks and strokes. By reducing oxidative damage and inflammation, this substance helps to prevent or slow down the process of this condition.
6.Reducing the Risk of Atherosclerosis
Oleuropein is directly related to improving cholesterol profiles. It may help lower levels of LDL, often referred to as bad cholesterol, while increasing levels of HDL, known as good cholesterol. Maintaining good and healthy cholesterol levels, oleuropein powder reduces the risk of arteriosclerosis and the possibility of heart attacks and strokes.
7.Diabetes Control
The anti-glycemic effect of oleuropein is very important in diabetics. This substance will prevent the increase in blood sugar and oxidative activity caused by diabetes. Accordingly, the administration of this substance is known to be useful for the prevention of diabetic complications that are related to oxidative activity.
8.Antiviral Effects of Oleuropein
Based on studies, the benefits of oleuropein are claimed to be strong antiviral activities against herpes mononucleosis, hepatitis virus, bovine rhinovirus, canine parvovirus and feline leukemia. Also, oleuropein has shown strong antiviral activity against respiratory obstruction virus and parainfluenza type 3.
9. Support the Immune System
As you know, the immune system plays a major and important role in defending the body against viruses, bacteria and maintaining the overall health of the body. Research has shown that this substance has immunomodulatory properties, that is, it is able to optimize and control the immune response.
The production of immune cells such as lymphocytes, macrophages and natural killer cells is necessary to fight infections and kill abnormal cells, and one of the benefits of oleuropein is to stimulate the production of these cells.
By strengthening the immune system, the duration and severity of diseases will be reduced and the risk of complications related to infection will be reduced.
10. Anti-Aging Effect and delaying its process
Natural fibroblasts in humans multiply due to genetic and environmental factors and aging. What causes aging and wrinkles on the skin is the presence of free radicals in the sunlight. In fact, mitochondria are damaged by oxidative damage and this action leads to aging in people.
These damages cannot be completely eliminated; Because they can disrupt the function of cells. Mitochondrial membrane is sensitive to free radical attacks and neurodegeneration will continue.
One of the best ways to fight and prevent this damage is to use compounds containing oleuropein.
This substance can help slow down this process by neutralizing and controlling AD, which is the cause of age-related diseases in the body.
last Word
Oleuropein, which is obtained from the leaves of the olive tree, has strong antioxidant and anti-inflammatory properties and has many benefits for achieving health and improving body conditions. This natural combination protects cardiovascular health and strengthens the immune system.
Other benefits of oleuropein include taking care of skin health and reducing the aging process.
Research and studies continue to fully understand the uses and mechanisms of oleuropein’s effect, and so far promising evidence has been obtained of the capacity of this substance as a complementary approach to increase the overall health of the body and reduce the risk of various chronic diseases.
Note that as with any dietary supplement or other natural treatment method, it is very important and necessary to consult a doctor and specialists for proper dosages and instructions according to the conditions of each person.
Sources:
sciencedirect
wikipedia